Stem Cell Therapy Explained: How Regenerative Medicine Is Changing Pain Treatment
Stem cell therapy and regenerative medicine are changing how we treat chronic pain, arthritis, joint damage, and degenerative conditions. In this exclusive interview, Dr. Ruben Timmons explains how stem cell treatments, birth tissue therapy, and orthobiologics may help patients reduce pain, improve mobility, and potentially avoid surgery.
We discuss:
• What stem cell therapy is
• Birth tissue vs your own stem cells
• Knee, shoulder, spine & joint treatments
• Pain management without opioids
• How regenerative medicine works
• Stem cell injections explained
• Who is a good candidate
• Research & clinical outcomes
• Safety and FDA guidelines
• What to look for before treatment
This conversation explores the future of regenerative medicine and how cellular therapy may help the body heal naturally.
Listen to the Interview!
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Full Episode Transcript
Hi friends, Jean Valentino. Welcome back to another episode of Gene Valentino’s Grassroots Truthcast. Here at the
Grassroots Truthcast, we’re here in the offices of Dr. Ruben Baracall Timonss in Pensacola, Florida. Uh Dr. Timonss comes
to me uh through my wife in fact who had a targeted response that was necessary
in her shoulder and her neck that required stem cell treatment. Yes,
that’s right. That’s what we’re going to talk about today is the science and technology, the application administration of stem cells in the human body right after this.
Hi everybody, I’m Bianca Delarza and you have to check out Jean Valentino’s Grassroots Truths Cast podcast. I was a guest. He has the best guests always.
Check him out. Relationships matter because people buy people. And that’s why I buy Eddie Xarin Insurance
of the Xarin Insurance Agency in Pensacola, Florida. A family-owned business with over 50 years in the
business. And they treat people the right way. From homeowners insurance to contractor’s insurance, condo insurance,
commercial insurance, all the different coverages that are out there, and of course, auto insurance. They’ve got you covered. They worry about you first.
You’re more than a policy number. You’re a person who they’re watching out for,
not when the sun is shining, but after the hurricane has left. If you want real service with real savings, contact Eddie
Zerin at the Eddie Xarin Insurance Agency. www.zarins insurance.com.
Give them a call today. You’ll be glad you did when you do.
Hi friends, welcome back. And I’d like you to meet my my guest today, Dr. Ruben Baral Timonss, Pensacola, Florida. Thank you for joining me.
Thank you for coming.
This is very interesting, doctor. You’ve come I want a little bit about your background first. We have so much to talk about. This whole concept of stem
cell therapy and research related there too to me is so interesting. Uh, I’m in
my early 70s and I think the science and technology of the future h has transformed the way we think about aging
and living and um, you bring to the table uh, a a solution. It’s been around
and I’ve heard a lot of people talk about it specifically. Can you describe what’s unique about you and hear what
you’re doing in the panhandle of Florida related to stem cell research and therapy?
Yes. Um my interest began uh with research in the country of Panama. Um I
was u the head of science, technology and innovation for that country. And when we initially started, I recognized
a group that was doing stem cell uh infusions and injections. And that
greatly interests me. So what I did to bring the standard up to what we would expect here in the United States is
establish an internal review board to approve the subjects that were going to be tested or that were going to receive
these injections or infusions. And then that would allow the the entity to
submit their findings and their data to clinical trials.gov go here in the states or here in the states. Uh they were in
Panama, but to to at least have the data at a high level where it could be uh
viewed and and valued by any other physician or any other practitioner. Um
the the concept was with this we would demonstrate what’s called a phase one or
trial um uh a safety trial uh showing that it would be safe and showing that
the outcomes were very beneficial. Um so that’s what got me interested. Well,
talk to me about your background just a bit as it relates to where you’re working now and then dovetail into
what do people think uh stereotypically think about stem cell therapy as opposed
to what you’re doing now which makes it more unique.
Yeah. Initially here in in the US there was the FDA set a standard a rule that
under a 361 guidance meaning though even though it wasn’t FDA approved you could
still utilize birth tissue if it wasn’t manipulated and used for homologous use.
So what I did was started some studies,
a retro uh review, a retro study review that demonstrated persons with, for example, knee osteoarthritis,
which was in its terminal stage, how they would respond to uh placenta uh
membrane. and the outcomes were outstanding and it again demonstrated safety and it was published on two
different trials uh or in two different studies. So this really began the
interest and and now uh in 2018 uh there was a law that was signed into
effect that allows right to try as long as these conditions were chronic and
they had failed all other uh interventions and people didn’t have to
live with this condition or chronic pain uh for the rest of their lives.
This is jux to the approaches that most physicians in the states have been have
been using to handle pain management. In this case, this becomes a new avenue or a new a new solution.
Yes. What what happens is that under the traditional manner uh people take non-steroidal anti-inflammatories,
maybe some steroids, maybe some opioids, and finally surgery.
All of which doesn’t necessarily remedy uh the pain.
And it really does not look on u the tools that the why we are degenerating
and the tools that are needed to make a condition that is debilitating more
healthy. And this is precisely what birth tissues, stem cells, um, and some
of the other, uh, procedures or what’s called autotogus use of PRP A2M, for example.
Okay, watch out. Okay,
there go those acronyms again. P A2M is plasmarrich protein alpha to macro globulin
bone marrow and fat cells of the person’s own body.
Yes. As opposed to cells from a placenta. A placenta or earth tissue.
And the difference to me it’s a difference without distinction. But from your point of view, what is the difference in this cell of a placenta,
amniotic fluid, the umbilical cord distinguished from you taking cells out of my body and then putting them back in my body?
Um, it’s pretty simple in the fact that if I use your cells, uh, they’re 70
years old and they’ve been exposed to everything that’s happened to you in life that has caused oxidative stress
that has and plus as we age the amount of stem cells produced are much much less in a birth tissue.
uh the regenerative ability is 200fold what we would do uh
with our own cells in certain cases. Um but as we age uh that ability decreases.
So the amount of actually stem cells that would be harvested from your body in bone marrow, fat, blood or otherwise would be much less and less effective.
Can you uh measure or distinguish the uh success uh of of an of your own tissue versus um birth tissue?
I think a lot depends on a person’s age.
Um younger persons, athletic persons respond pretty well to autogus use,
meaning from their plasma or for from their fat or bone marrow. Um, and
older persons or persons that have been exposed more to oxidative stress, poor diet,
um, respond better to, uh, the the birth tissues.
You’re originally from the country of Panama and, um, you were a consultant
physician down there with the government and the legislature. you had, correct me if I’m wrong, provided protocols,
uh, proposed protocols for a process of bringing um, stem cell technology and
the solution to the forefront through the government process. How did that happen? How did that work out?
Um, a lot of push back initially. It wasn’t really easy, but I think the the key was establishing an internal review
board that could be the uh be the guardian of the subject that was going
to undergo the the uh intervention or the application of stem cells. And then
as long as data was produced uh and kept that that would show the outcome as
being scientifically generated as opposed to just
um hearsay or testimonials. Uh testimonials are fine, but it’s really
the the the data accumulation that’s the most important. So this was the way that
it was brought to the forefront and and uh with actually successful trials.
Uh we are in an era under the Trump administration where Robert F. Kennedy Jr. and his involvement with the
department of health and human services has um done some uh transformative things overnight in many areas. Uh diet
being one of them. Um, but what has his administration been helpful in opening the door for more
practical progress in the future of stem cell research
in the way uh that um with diet uh you know we’re subject to poor diets just
because it’s in our culture with processed foods etc. uh I think which he which he had a significant uh input in changing recently.
I think it’s one of the ways that we can care for ourselves and one of the ways that we can help u stave off the degenerative process.
Is that an American issue? Is it this bad elsewhere?
It’s bad in a lot of places around the world.
Yeah. Around the world. uh in Latin America included.
Yeah, we get a bad rap for having poor standards in certain ways. We we’re innovative and advanced in so many ways,
but we also are accused of being um abusive to our bodies in the way we we comment.
No, I mean it’s true. I mean, it’s not there’s not one magic wand that’s going to make somebody better. You have to you
have to really commit yourself to there’s no shortcut to exercise to meditation
and to good diet. And as long as we’re able to balance that uh then we can diminish
oxidative stress and things that break down tissues. And for example, you know,
even diabetes, we have a tremendous amount of persons with type
2 diabetes, which is very detrimental to the immune system and intends to make things worse along with other things.
overweight u on uh is is uh responsible for a lot of the joint pains hips, backs, knees,
ankles because u and losing weight is a process and even with surgery they ask
you to the success of a hip replacement for example if you have to get there is lowering your weight instead of having
being obese or mor mor morbidly obese which you wouldn’t be the best candidate for so we have to take some responsibility
in in what we do and this um I think the advent of cellular
treatments um is opens a window uh of time that we can
recalibrate or reboot ourselves in that uh we can now adjust our diet we can lose weight. We can start to exercise
because we’re going to have the energy and the uh state of being painfree or
diminished pain so that you can do the things necessary to uh improve your overall health. It seems your approach,
correct me if I’m wrong, is more toward um the real solution of cellular regeneration
that fixes the problem wherever it is in the body. Um which alleviates the pain
presumably as opposed to the operative procedure of cutting, excising
um or shunting uh pain that’s in the body. Now stem cells distinguishes
itself because you’re trying to let the body use its natural function to cure itself to heal itself. Yes. I mean,
how’s your success on that? What do you have any at the on the back of the envelope numbers that you can throw out about what what the success is like in this new arena?
Uh it’s hard to say. I mean it would be uh there’s a lot of data out there u and
depends on the patient. If one is really deconditioned or obese or have a lot of
underlying other diseases then the outcomes aren’t as good. In someone that’s relatively healthy the outcomes
are are very significant in that they can avoid surgery altogether.
and uh again get back to their normal activities.
I wouldn’t have believed it if I didn’t see it, but uh you worked on my wife.
She gave me permission to tell the story. Uh you worked on my wife’s knee,
I believe it was, and injected uh stem cell therapy into the knee joint,
something between uh where was it? Under the kneecap somewhere. And um uh she had
been in pain limping for a long period of time. She got off your table and was hopping around. I actually got worried
that she might have hurt herself. She felt no pain. She had tears in her eyes.
I didn’t know if you did something good or something bad. No offense, but I don’t get too many patients jumping off
a table, hopping around. So I it was a concern and she was joyful for what you
had done to her. And that’s why we’re here. One of the reasons we’re here today is that there’s something you’re doing here that needs to get out. And the more
I researched this, the more I realized you’re competing by differentiating in a
world of regulation, in a world of um uh of of administrative oversight and
preference that has to be given towards drugs or procedures where at times the
patient’s uh safety and concern isn’t first. Even though that’s the mantra, they’re saying it is, but it’s not.
There’s things going on in your world that that are not um necessarily formidable or in the best interest of
the patient initially. I noticed that isn’t true here. Here, you’re doing everything possible to make sure the patient is well when they leave here.
uh how did you have the same sort of success with other patients the way I witnessed with my wife?
Yes. And these this was elucidated in my publications where uh and I used um
amniotic membrane as and uh as the orthobiologic and uh with that the for knees the the
the outcomes were were outstanding and these were measured as far as function
something objectified uh with using the with using pain and and function and
these patients improved uh in their function. uh they were able to transition off their
non-steroidal anti-inflammatories and in most cases off their opiates because that’s been the usual pattern
that we’ve used for years in in this country is anti-inflammatory maybe opiate maybe some steroids but steroids
just block the process as whereas cellular treatments um birth tissue do
and u actually interferes and stops the process of
degeneration and these are the proteases the enzymes that tear down cartilage
after a while. Um on the other hand steroids do work but it’s been demonstrated that continuous use of
these steroids actually does more harm than good if used over longer period of time. I I had taken a steroid at one point. Is this a degeneration of tissue?
Is that what’s going on?
Well, it’s with the steroid.
No, with with the steroid, it’s not necessarily the degeneration of tissue.
It will help you because it’s a potent anti-inflammatory that u that blocks the process. um but u
as repeated use would cause further damage uh to the tissue and to the to the cartilage.
So what uh are you researching now? I know there’s the application administration of of
material uh stem cell material for the patient but is there a research approach you’re taking now to uncover some new pathway?
Um there are some research that we’re doing and uh right now I’m working with a
a a company or that looking at rheumatoid arthritis arthritis and I believe it’s a phase two where it
we’re starting to get some really good results and uh part of this is um now
with this uh you can do you can utilize um IV infusions as well as targeted u
injections uh into the specific area of pain like whether it be the the back,
the wrist, uh anything that rheumatoid arthritis may affect uh because the
effect that these uh cells or this uh tissue has on the process of inflammation.
Um, with that we hope to have more data to justify
uh the use in in other types of illnesses or uh that cause pain
that have failed all other avenues of treatment and is pretty debilitating. Is there anything in your world that you’re
working on either as a procedure or a product that’s considered patentable right now? Are you securing
uh a technique that might be unique or I don’t think so. It’s pretty standard.
It it’s standard um and that those of us who uh do these applications
uh it has to be targeted In other words, in order to do something in the spine, you have to do it under
fllororoscopic guidance. You have to see where you’re placing this medication. If it’s in any of the joints, it has to be done under ultrasound. To me, that’s a
standard of care. To do it blindly is really not doing the full service uh to a patient. That is one of the issues
that was always u something of concern to me that I’ve heard about from other people uh who’ve seen other doctors as
well and that is they are going in blind with the injection as opposed to what you’re doing. You’re you’re actually
looking in there through ultrasound or whatever and uh and making sure that the injection of the stem cell material is
precisely placed at the point of pain. I know the way you handled the rotator cuff for my wife and the shoulder area
was obviously targeted just as the knee was. But um it’s very interesting you
know Dr. Payne reveals itself to everybody differently and uh they’ve got we all had pains in all parts of our
body. Uh is there any focus you have or what do you tell people with pains in different parts of their body that we
haven’t talked about? But I mentioned the knee, I mentioned the shoulder, but the vertebrae and the neck,
the the spine, any um articulation, any joint u that is inflamed or whether it being the spine,
whether it being the shoulder, elbow, hand, uh knee, foot, or hip. um and
anywhere from damaged tendons to uh joint involvement itself. Uh these are
all and and again I’ll emphasize persons that have found no other means and maybe
in some of these cases surgery wouldn’t help and they’re told you have to live with this and that’s not necessarily true.
Worked on any professional athletes? Yes.
Yeah. uh uh joints and tendons and yes,
you know, I I think there’s different approaches for care and um I guess some per one person may come in and think
they’re well, but it may be a recurring uh number of visits required. Is it a oneshot deal or do you have um a
recurring treatment plan? How does it work? U typically uh what I tell patients that if it’s spine related or
whatever it’s one and done instead of a multiple uh scenario where you have back pain you
get you have two injections in the spine and then you visit in the office and then you do a radio frequency ablation
which in and of itself over time and over repeated use may cause some
atrophy of some of the muscle in the back. Um with the bio the the
orthobiologic um it’s typically done in one setting.
Typically we’ll get one to several years relief uh depending on the condition
depending on the compliance by the individual if they no pain pills or anything. this is this is one and done.
Well, it’s a chronic disease and people can usually say, “Hey, I I’m more functional. I have a little pain, but
I’m not taking my pain medicines uh now.” And so that’s what we hope because we know that a lot of these drugs that
we use cause systemic problems such as high blood pressure, kidney gut disease.
So, uh, I’m not Most people want to get off their medications because they do have terrible side effects. Yeah.
Whereas, uh, the orthal biologic does not.
What’s the procedure when the patient’s coming in? I I I’m kind of curious as to what’s actually happening.
Is this like a foreman in a job site, the product?
Yes, in a way, it is. And what happens is that when this tissue the orthobiologic is placed in an
inflammatory site, it’s like having a construction site wherein u this you’re
getting orders and it’s it’s about signaling other cells and other uh other
cellular products, exoomes, all these things that we get into. and with that
repair and allow your body to self-repair also. Um, a lot of these
stem cells that or stem cells that are injected uh are sequestered in the lung.
So it’s it’s the proteins, it’s the signaling, it’s this this foreman that’s
sending out the signals um and getting all the right um
delivery of of anti-inflammatory medications. It’s you have the whole pharmacy at work.
I see. instead of just one particular drug or one particular part of a of a stem cell product.
So, it’s more than just a drug. It’s it’s really the the transmission transmission of messaging by the stem
cell product that’s triggering um regeneration of other cellular activity in the body.
Yes. the re regeneration if if if as well as a prolong anti-inflammatory
and amniotic fluid um placenta and uh the umbilical cord materials
uh are are more triggering are more successful than the use of aged cells within one’s own body.
Correct?
because of the what is it the signaling coming off that younger that younger product.
Yes. And it’s overall overall potency that it’s not it’s not been exposed to
again oxidative stress. It’s a young cell.
You got a system here that seems to be working. Uh it eliminates a lot of people taking a lot of drugs.
uh is that your impression of the outcome of your your treatment?
Yeah, we in in the the publications we measured the use of drugs,
anti-inflammatories as well as decreasing from opiates and I think every individual that comes
through here want to get off these medications because it doesn’t make them feel good uh because they have other side effects from uh the medications.
What are people experiencing when they leave here? They they feel success.
Um it depends everybody. Some persons uh have almost immediate relief really
and others it may take up to uh 12 weeks more of a gradual onset of of pain
relief of improved function. But um um and that’s just a variability between patient.
We know what your success has been by the level of responses we’ve heard. Uh but where what’s your appetite? What’s your what’s your interest? Where would
you like to see the future of stem cell research and therapy go?
I’d like to see it available for everyone. Is it restricted in some way now?
Oh yes. I mean, even with this um law now that’s been signed into existence,
it it’s specific in that it has to be chronic pain and everything else that failed. And what we’d like to see is
catching the disease early as opposed to waiting till it becomes too chronic. Um,
preventative medicine in that fashion.
What a concept. That’s what the original intention of insurance and many other technologies were supposed to be
providing. Not the protection of certain vendors, folks, but rather the initiation of research and development
to prevent uh injury or uh sickness in the first place. Um did I put words in
your mouth or is that really that that rings the bell?
Okay. That is uh that’s the that’s the goal is to um treat things before they get chronic,
intervene with the patient, educate the patient on the the things that they have to take responsibility for in order to
uh prevent further damage to their to their body.
So maybe living to 130 isn’t that crazy of an idea after all. Uh uh it seems that what you’re doing is helping the
body nourish itself and live longer and who could ask for a better therapy. This has been very interesting. Doctor Dr.
Ruben Timonss is with us from the panhandle of Florida and uh he’s his specialty is stem cell research and
therapy. And when we return, you can give your website, your related contact information. Let’s go take a tour and see what’s going on right after this
message. Relationships matter because people buy people. And that’s why I buy
Eddie Xarin Insurance of the Xarin Insurance Agency in Pensacola, Florida.
A family-owned business with over 50 years in the business. And they treat people the right way. From homeowners insurance to contractor’s insurance,
condo insurance, commercial insurance,
all the different coverages that are out there, and of course, auto insurance.
They’ve got you covered. They worry about you first. You’re more than a policy number. You’re a person who
they’re watching out for, not when the sun is shining, but after the hurricane has left. If you want real service with
real savings, contact Eddie Zuran at the Eddie Xarin Insurance Agency. www.zarins insurance.com.
Give them a call today. You’ll be glad you did. When you do
so, doctor, what do we have here? Uh this is an ultrasound machine and basically what it does it allows us to
look at any orthopedic joint uh that may be compromised or that we’re thinking of injecting an orthobiologic.
So the patient is usually lying down or sitting up and we’re able to visualize in live time and direct uh the product to that specific area.
So it’s at least a twoman job here. Yes, I have an assistant.
Yeah, this would be the standard application room for that.
Yeah, we have another room next door that we would do the same. We have two rooms that are ready to go.
I couldn’t help but notice this um this filing uh uh that you were involved in from the Journal of Regenerative and
Biology and Medicine uh going back a few years. 19 Where are we? 2020.
2020. There it is. You want to describe what this is about?
Well, we looked at uh 40 uh subjects knees and measured uh their pain scales,
measured their function as a as the WMAC, which is a a functional scale and
also their ability to uh wean off medications.
And um the the results were pretty outstanding in that u to come off medications went from something like 80%
down to 25%.
Through the application of stem cell after the application and their functional uh scales as as proposed by
the WMAC measurements improved uh very significantly as well as their overall pain skills.
I’m so interested in hearing more too in the minutes ahead about the the transition that’s occurred in legislation and throughout the country
about making things easier for not only the application of stem cell therapy but other related therapies that that are
associated with it. But this is a kind of room that there’d be at least two of you, right? There’d be the room of there’d be the someone wanting the
ultrasound and then you’re applying the stem cells. Correct.
Interesting. Let’s go see the main uh room you you you do a lot of your work in.
Wow. I didn’t realize you had all this equipment here, doctor. How is this different than the other room?
Uh this is where we do uh procedures uh application of orthobiologics.
Um usually with on the spine, sometimes with the hip, sometimes with the shoulder, but mostly spine. And this
allows us to pinpoint uh and precisely where the lesion or the problem is.
Whether it be in the spine, the joints around the nerve tissue, we’re able to visualize this in lifetime. Uh with
this, we’re 100% sure that we’ve placed the orthobiologic in the correct space.
uh this enhances a person’s ability to then get better and uh hopefully become more and more functional.
Back in 2018, the United States government u under President Trump and the federal legislation came forward
modifying the way health care is delivered in the states, making it easier for you here now, right? Well,
here and in in Texas because uh they’ve recognized that uh this is a a new
avenue uh for persons to take and that the orthobiologic whether it be stem
cells or birth tissue has a huge impact on on healing and and function.
Well, very interesting. Hey, let’s go out front and see how people could get hold of you.
Great being with you today, doctor.
Before we finish, what should people be looking for? What are the things they should uh look for or be worried about before considering stem cell therapy?
Um about three things that um are very important. one that the tissue bank
where the tissue is acquired um is FDA
registered and at the same time meets criteria of the 361
designation uh minimally manipulated and that’s what 361 means. Yeah. and used homologously. And third,
that the provider has a very in-depth uh consent form so the patients know. And
uh by and by having these regulations placed on the registered tissue bank, uh
you can be more assured that what the the product you’re re receiving is safe.
And folks, you’re going to see that on the website which is at the bottom of the screen and the phone number. So look for it there and you can browse around on Dr. Timman’s site. And when people do
contact you, what’s the procedure they go through for qualifying?
Uh usually we we will send them a a form to fill out uh out outlining all their
medical issues and we will review that to determine whether or not they are a a
good candidate. And um this involves uh their medical history, any diagnostic
tests that have been done. So we have all the information um at hand when they
show up for an appointment. Uh there’s a lot of people out there claiming they’re involved in stem cell therapy, but
they’re um uh they’re not renegades or cowboys, but they’re certainly not following protocols that um obviously
I’ve seen you display today. Uh what what’s the difference? What what should the consumer be looking for in terms of
that kind of care? They need to ask those three questions that I just just say the whether they’re the tissue bank is
FDA registered and whether they’re using the tissue or the biologic as outlined
being minimally manipulated and that all happened back in legislative change in 2018.
I think it was under the Trump administration where uh things became more procedural and more the gateway opened for more uh research development and administration.
That’s correct.
Dr. I can’t thank you enough for joining me today on the Grassroots Truth Cast.
This has been a pleasure. uh we have had we’ve covered a lot of ground and uh I really hope um you the audience get on
his website or call him directly uh to uh book an appointment and between you and the doctor determine for yourself uh
the applicability uh of stem cells therapy for your for your care.
Thank you again. You’re very appreciate your time and to you I thank you for joining us on another episode of the Grassroots Truth Casts. See you soon.
Heat. Heat.
Relationships matter because people buy people. And that’s why I buy Eddie Xarin
Insurance of the Xarin Insurance Agency in Pensacola, Florida. A family-owned business with over 50 years in the
business, and they treat people the right way. from homeowners insurance to contractor’s insurance, condo insurance,
commercial insurance, all the different coverages that are out there, and of course, auto insurance. They’ve got you covered. They worry about you first.
You’re more than a policy number. You’re a person who they’re watching out for,
not when the sun is shining, but after the hurricane has left. If you want real service with real savings, contact Eddie
Zerin at the Eddie Xarin Insurance Agency. www.zarins insurance.com.
Give them a call today. You’ll be glad you did when you do.













